A while back, inspired by the CSS Zen Garden, I modified my Blogger template to use entirely CSS-based design. That is, I can know update the layout instantly simply by replacing the stylesheet file used by template (like now!)
The new layout uses up a wider screen space, but I think it's neat. The lighter colors are easier on my tired, computer-strained eyes. Hopefully, this new CSS-based design allows me to do more experimentation and improve my ability to design web UIs.
Speaking of web UIs, I only recently saw the new look for Yahoo Groups. Similar to the change for the main Yahoo site, it focuses more on lighter colors now, and has significant usage of font coloring to show important points. I like it. Maybe they'll improve the Yahoo Mail layout next.